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Isoflurane Administration as a Method for Neuroprotection in Organophosphate Poisoning (HJF 620-22 and HJF 441-16)
Organophosphate-based chemical agents (OPs), including nerve agents and certain neurotoxic pesticides such as paraoxon, are potent acetylcholinesterase inhibitors that cause severe convulsions and prolonged seizures, including progression to status epilepticus, potentially leading to irreversible central nervous system (CNS) damage if not treated promptly....
Published: 5/9/2025   |   Inventor(s): Aryan Namboodiri, John Moffett, Narayanan Vasudevan
Keywords(s): CNS, Neuroprotection, Organophosphate, Pesticide Poisoning, Seizure, Status Epilepticus
Category(s): Therapeutic, Medical Device