The Henry M. Jackson Foundation for the Advancement of Military Medicine

Advancing Military Medicine

Search Results - nano-particle

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Novel, Cross-Sarbecovirus Neutralizing and Binding Monoclonal Antibodies (mAbs) (HJF 660-23)
The repeat emergence of SARS-CoV-2 variants of concern (VoC) with decreased susceptibility to vaccine elicited protection highlights the need to develop vaccine candidates with broad protection. Current invention identified six neutralizing antibodies with broad sarbecovirus cross-reactivity. This finding has applications towards developing next-generation...
Published: 5/9/2025   |   Inventor(s): Kerri Lal, Shelly Krebs, Samantha Townsley, Michael Gordon Joyce, Vincent Dussupt
Keywords(s): Antibody, Coronavirus, Cross-Reactivity, Ferritin, Infectious Disease, Nano-particle, Neutralizing Antibodies, Respiratory, Sarbecovirus, SpFN, Spike Proteins, Vaccines, Variants, Viral
Category(s): Research Tool
Vaccines against SARS-COV-2 and other Coronaviruses - (HJF 569-20 & HJF 635-22)
Researchers at HJF and the Walter Reed Army Institute of Research (WRAIR) have developed novel vaccines comprised of fusion proteins; Ferritin nanoparticle and antigenic coronavirus peptide(s). These fusion proteins generate simultaneous protective neutralizing immune responses against coronaviruses and their variants. Applications and Advantages Innovation...
Published: 3/14/2025   |   Inventor(s): Kayvon Modjarrad, Michael Gordon Joyce
Keywords(s): Coronavirus, COVID-19, Nano-particle, SARS-CoV-2, Self-Assembly, Vaccines, Variants
Category(s): Diagnostics, Therapeutic