The Henry M. Jackson Foundation for the Advancement of Military Medicine

Advancing Military Medicine

Search Results - infectious+disease

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Novel, Cross-Sarbecovirus Neutralizing and Binding Monoclonal Antibodies (mAbs) (HJF 660-23)
The repeat emergence of SARS-CoV-2 variants of concern (VoC) with decreased susceptibility to vaccine elicited protection highlights the need to develop vaccine candidates with broad protection. Current invention identified six neutralizing antibodies with broad sarbecovirus cross-reactivity. This finding has applications towards developing next-generation...
Published: 5/9/2025   |   Inventor(s): Kerri Lal, Shelly Krebs, Samantha Townsley, Michael Gordon Joyce, Vincent Dussupt
Keywords(s): Antibody, Coronavirus, Cross-Reactivity, Ferritin, Infectious Disease, Nano-particle, Neutralizing Antibodies, Respiratory, Sarbecovirus, SpFN, Spike Proteins, Vaccines, Variants, Viral
Category(s): Research Tool
Malaria Vaccine - (HJF 474-17)
A novel composition of malaria vaccine technology is available for licensing from HJF. A Phase I clinical trial has been completed and results have shown the safety and efficacy of this vaccine composition in humans. Applications and Advantages Novel immunogens and compositions for malaria vaccine Significant clinical efficacy demonstrated in humans Fully...
Published: 5/29/2025   |   Inventor(s): Zoltan Beck, Carl Alving, Gary Matyas, Sheetij Dutta
Keywords(s): Infectious Disease, Malaria, Prevention, Therapeutics, Vaccines
Category(s): Therapeutic