The Henry M. Jackson Foundation for the Advancement of Military Medicine

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Search Results - edward+mitre

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Complex Natural Homogenates for Treating Allergies and Autoimmune Diseases (HJF 357-13)
Studies in humans and animals have demonstrated that infection with parasitic worms is protective against a range of chronic inflammatory diseases. These include inflammatory bowel disease, environmental allergies, asthma, and autoimmune diseases such as Type 1 diabetes, multiple sclerosis, and rheumatoid arthritis. Parasitic worm infections modulate...
Published: 12/8/2025   |   Inventor(s): Edward Mitre, Marina Torrero, Belinda Jackson
Keywords(s): Immune Balance, Natural Supplement, Nutraceutical Development, Safe Immune Modulation, Type 1 Diabetes Prevention, Worm Extract
Category(s): Therapeutic
Filarial Intestinal Antigens as Vaccine Candidates and Testing in Novel Animal Model of Filariasis - (HJF 378-14)
Introduction Filariae are tissue-invasive parasitic nematodes that cause human diseases such as lymphatic filariasis, river blindness and African eyeworm; affecting over 200 million people worldwide. In addition to human disease, filarial parasites infect dogs and cats causing heartworm infections. Currently, no vaccine exists to prevent either human...
Published: 10/29/2025   |   Inventor(s): Edward Mitre, Christopher Morris, Sasisekhar Bennuru, Thomas Nutman
Keywords(s):  
Category(s): Research Tool, Therapeutic
Novel Vaccine Enhancers - (HJF 642-23)
Researchers at Henry M. Jackson Foundation (HJF), Uniformed Services University of the Health Sciences (USU), and Leidos Biomedical Research, Inc. (Leidos) have developed improvements to the effectiveness of mRNA vaccines. Such enhancements could reduce the number of doses needed for maximal protection, enhance vaccine durability, and reduce associated...
Published: 12/8/2025   |   Inventor(s): Edward Mitre, Elizabeth Graydon, Stephen Anderson
Keywords(s): mRNA, Therapeutics, Vaccines
Category(s): Therapeutic
Preventing and Treating Filarial Disease - (HJF 470-17)
Filarial worms are thread-like parasites that cause severe damage to the lymphatic system as manifested by painful and abnormal swelling of body parts. Current strategies to stop infection includes annual Mass Drug Administration (MDA) to the entire at-risk population (human and animal) for 6-10 years. However, the drugs used currently have limited...
Published: 12/8/2025   |   Inventor(s): Edward Mitre, Alexander Flynn, Christopher Morris, Thomas Nutman, Sasisekhar Bennuru
Keywords(s):  
Category(s): Therapeutic