The Henry M. Jackson Foundation for the Advancement of Military Medicine

Advancing Military Medicine

Search Results - diagnostics

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A Urine-based Method to Isolate and Detect Prostate Cancer Cells Using Immunohistochemical Analysis (HJF 247-10)
Background Current methods for detecting prostate cancer can lack sensitivity and specificity, particularly when analyzing low concentrations of cells in biological samples. Existing diagnostic techniques may require invasive procedures or fail to efficiently recover and identify cancer cells from urine samples. There remains a need for improved methods...
Published: 7/15/2026   |   Updated: 5/28/2026   |   Inventor(s): Shiv Srivastava, Gyorgy Petrovics, Shyh-Han Tan, Kristen Nickens
Keywords(s): Biomarker, Cancer, Cell Line, Diagnostics, Immunohistochemistry, Prostate Cancer, PSA
Category(s): Diagnostic
Use of Machine Learning Models for Prediction of Clinical Outcomes (HJF 529-18)
Background Individuals exposed to physical trauma, including battlefield injuries and major accidents, are at elevated risk of severe complications. Existing diagnostic approaches can make it difficult to accurately quantify clinical risk and guide treatment decisions, particularly in environments where advanced diagnostics are unavailable. Early identification...
Published: 7/16/2026   |   Updated: 5/28/2026   |   Inventor(s): Seth Schobel-McHugh, Matthew Bradley
Keywords(s): Biomarker, Critical Care, Diagnostics, Machine Learning, Random Forest Model, Respiratory, Respiratory Distress, Sepsis, Traumatic Brain Injury
Category(s): Diagnostic
Rapid, Point-of-care Sepsis Mortality Prediction System – (HJF 655-23)
Researchers at the Henry M. Jackson Foundation for the Advancement of Military Medicine (HJF) have developed systems and methods for predicting sepsis mortality risk using biomarker data and clinical parameters. Applications and Advantages Enables early and accurate prediction of sepsis mortality risk. Supports improved clinical decision-making...
Published: 6/22/2026   |   Updated: 5/21/2026   |   Inventor(s): Danielle Clark, Joost Brandsma, Joshua Chenoweth, Deborah Striegel
Keywords(s): Clinical Decision Support Systems, Critical Care, Diagnostics, Gene Expression Assays, Machine Learning, Point of Care, Sepsis
Category(s): Diagnostic
Vaccines Against Fentanyl and Fentanyl Analogs - (HJF 561-19)
A technology related to novel fentanyl hapten compounds and their use in the preparation of vaccines against fentanyl and fentanyl analogs is available for licensing. Applications and Advantages Novel compounds for use as vaccines against fentanyl and analogs High immunogenicity that generates fentanyl specific antibodies to reduce its distribution...
Published: 7/1/2026   |   Updated: 3/27/2023   |   Inventor(s): Gary Matyas, Oscar Torres, Kenner Rice, Eric Bow, Agnieszka Sulima, Arthur Jacobson
Keywords(s): Antibodies, Diagnostics, Fentanyl, Therapeutics, Vaccines
Category(s): Therapeutic
Shark Antibodies and Shark-Derived Binding Domains Specific for the SARS-CoV-2 Coronavirus - (HJF 581-20)
HJF scientists have developed a series of single variable domain antibodies (nanobodies or VNARs, derived from nurse sharks) specifically targeting SARS-CoV-2 and other betacoronaviruses, thus providing unique therapeutics and diagnostics for COVID-19 and possibly other betacoronavirus infections. Applications and Advantages Fully sequenced, grafted...
Published: 1/12/2026   |   Updated: 2/2/2023   |   Inventor(s): Michael Gordon Joyce, Kayvon Modjarrad, Helen Dooley
Keywords(s): Antibody, Coronavirus, COVID-19, Diagnostics, Sarbecovirus, SARS-CoV-2, Therapeutics
Category(s): Therapeutic, Diagnostic
Urine-Based Prostate Cancer Diagnostics - (HJF 485-17)
A technology for screening and diagnosing prostate cancer based on urine exosomes is available for licensing from HJF. Applications and Advantages Screening for and diagnosis prostate cancer with superior accuracy than the standard of care. Convenience of using regular urine sample that can be collected at home, as opposed to post-DRE urine sample. RNA...
Published: 7/16/2026   |   Updated: 2/2/2023   |   Inventor(s): Shiv Srivastava, Gyorgy Petrovics, Indu Kohaar
Keywords(s): Diagnostics, Prostate Cancer
Category(s): Diagnostic