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The Henry M. Jackson Foundation for the Advancement of Military Medicine
Advancing Military Medicine
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Diagnostic Tool for High-grade Serous Ovarian Cancer - (HJF 616-21)
Researchers at HJF, Inova Fairfax Hospital (IFH), and the Peter MacCallum Cancer Centre (PMCC) have identified orthogonal protein and transcript-based biomarkers correlating with Homologous Recombination Deficiency (HRD). This may lead to a companion clinical diagnostic
assay
to prioritize High-Grade Serous Ovarian Cancer (HGSOC) patients for targeted...
Published: 3/14/2025
|
Inventor(s):
Nicholas Bateman
,
Tamara Abulez
,
Thomas Conrads
,
George Larry Maxwell
,
Dale Garsed
,
David Bowtell
,
Ahwan Pandey
Keywords(s):
Assay
,
Biomarker
Assay
,
Companion Diagnostic
,
DDR
,
DNA Damage Repair
,
HGSOC
,
High-Grade Serous Ovarian Carcinoma
,
Ovarian Cancer
,
PARP Inhibitors
Category(s):
Diagnostics
,
Therapeutic
Immunogens and Vaccine Components Against HIV - (HJF 630-22)
HJF researchers have developed a novel vaccine strategy against HIV-1. These vaccine candidates are designed to elicit broadly neutralizing antibodies that could protect against a wide variety of HIV strains. Applications and Advantages Novel vaccine design approach that emulates the diversity observed in HIV-1 infections with multiple founder variants Vaccine...
Published: 3/14/2025
|
Inventor(s):
Morgane Rolland
,
Eric Lewitus
,
Hongjun Bai
Keywords(s):
Antibody
,
Assay
,
bnAbs
,
CD4
,
Env
,
HIV
,
Vaccines
Category(s):
Vaccine
,
Therapeutic
